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BioIntegral Surgical manufactures devices using the No-React® treatment. No-React® is a proprietary detoxification of glutaraldehyde-treated tissue, which provides improved morbidity and mortality outcomes for our patients.

More than 20 years of proven clinical experience with No-React® devices shows:

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  • Reduced toxicity

  • Enhanced biocompatibility

  • Dramatically lower rates of infection

  • Elimination of adhesion and calcification

  • Promotion of functional endothelial lining

  • Reduced mortality

  • Reduced complications and interventions

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